When we moved to the Dominican Republic, I quickly learned that dinner needed to be quick, adaptable, and filling—especially with kids coming and going from activities and ingredients not always easy to find. This Keto Buffalo Chicken Casserole became one of those back-pocket recipes I turn to when I need something spicy and satisfying. With its bold flavors and creamy texture, it hits the spot without spiking my blood sugar, and everyone from my teenager to my toddler devours it happily.
I remember the first time I made this casserole for a church potluck—one bite in, and a friend asked if she could take home leftovers for her husband. It’s that kind of dish.
A Flavor-Packed Keto Casserole
This Keto Buffalo Chicken Casserole promises a delightful mix of rich and creamy textures, making it a fantastic choice for those following a keto diet. The dish showcases tender chicken enveloped in a zesty buffalo sauce, all topped with layers of gooey melted cheese.
Every bite is a burst of flavor, combining savory elements that will satisfy cravings without the extra carbs. Whether it’s a weeknight meal or a gathering with friends, this casserole stands out for its simplicity and taste.
One evening, we served this to visiting friends from the U.S., and they were surprised to find such a familiar flavor in a Dominican kitchen—buffalo sauce is not a staple here, so I stock up whenever I can.
Ingredients That Shine
Crafting this casserole is straightforward, requiring common ingredients that are both nutritious and fulfilling. Shredded chicken forms the hearty base, while cream cheese and sour cream add richness, making every spoonful creamy and satisfying.
I often use rotisserie chicken when we have a busy day, but when I have more time, I cook and shred chicken thighs with bay leaf and garlic for added depth.
The buffalo sauce provides the essential kick, balancing the richness with a hint of spice, while the cheddar cheese on top creates a golden crust that further enhances the dish’s appeal. Fresh green onions not only add a pop of color but also contribute a subtle crunch to each serving.
Preparation Made Easy
Getting started on this casserole is quick and efficient. A mere ten minutes of prep time is all it takes to mix together the key components. The cooking process follows with a 25-30 minute bake time, allowing the flavors to meld beautifully.
Our oven runs a bit hot in the tropical climate, so I check it at 20 minutes to avoid over-browning the cheese—lesson learned after a few crispy-topped casseroles.
The result is a deliciously bubbly and golden creation that fills the kitchen with mouthwatering aromas. Once baked, letting it cool briefly helps achieve the perfect consistency for serving.
Serving Suggestions
This casserole is wonderfully versatile and can be served alongside various accompaniments. Fresh celery sticks provide a nice crunch that complements the creamy dish, while additional buffalo sauce can be offered for those who enjoy an extra kick.
For an even heartier meal, consider pairing it with a side salad or some low-carb veggies. The casserole can also be presented in individual servings for a more elegant touch at gatherings.
Nutrition Highlights
This dish not only pleases the palate but is also packed with nutritional benefits. Each serving contains a solid amount of protein, making it an excellent option for those looking to maintain a high-protein diet.
At just 350 calories per serving, with only 4 grams of carbohydrates, it aligns perfectly with keto guidelines, enabling you to enjoy comfort food without straying from your dietary goals.
Conclusion and Storage Tips
When it comes to leftovers, this casserole holds up well and can be easily stored in the refrigerator for a few days. Simply reheat in the oven or microwave for a quick meal.
We’ve even packed leftovers in insulated containers for a beach picnic—buffalo chicken by the ocean is a surprisingly great combo.
The rich flavors often intensify after a day, making it even more delicious. With its ease of preparation and flavorful outcome, this Keto Buffalo Chicken Casserole is a dish you’ll want to revisit time and again.
Ingredients
- 3 cups cooked shredded chicken
- 1/2 cup buffalo sauce (adjust to taste)
- 1 cup cream cheese, softened
- 1/2 cup sour cream
- 1 cup shredded cheddar cheese
- 1/2 cup green onions, chopped
- 1 teaspoon garlic powder
- Salt and pepper to taste
- 1 cup additional shredded cheese for topping
Ingredient Substitutions
- Buffalo Sauce: Use sriracha or a mix of hot sauce and melted butter if buffalo sauce isn’t available.
- Sour Cream: Greek yogurt works well and adds a protein boost.
- Cheddar Cheese: Try mozzarella for a milder flavor or pepper jack for added heat.
- Cream Cheese: Neufchâtel is a good lighter alternative.
- Green Onions: Use finely chopped white or red onion in a pinch.
Instructions
- Preheat the oven to 350°F (175°C).
- In a large mixing bowl, combine the shredded chicken, buffalo sauce, cream cheese, sour cream, garlic powder, green onions, and half of the shredded cheese. Mix well until all ingredients are evenly coated.
- Transfer the mixture into a greased 9×13-inch baking dish. Spread it out evenly.
- Top with the remaining shredded cheese.
- Bake in the preheated oven for 25-30 minutes, or until the cheese is bubbly and golden brown.
- Let it cool for a few minutes before serving. Enjoy your Keto Buffalo Chicken Casserole hot!
Cook and Prep Times
- Prep Time: 10 minutes
- Cook Time: 30 minutes
- Total Time: 40 minutes
- Servings: 6
Pro Tips
- Use freshly shredded cheese for better melting and fewer additives.
- Let the cream cheese come to room temperature for easier mixing.
- Add chopped celery or diced cooked bacon for extra texture and flavor.
- If your buffalo sauce is very spicy, blend it with a tablespoon of melted butter to mellow the heat.
- For easy cleanup, line your baking dish with parchment paper before adding the mixture.
Tip from Grammie Shirley
If you’re storing leftovers, press a piece of parchment paper directly onto the surface of the casserole before refrigerating—it helps prevent that rubbery cheese top from forming.
Nutrition and Serving Info
Estimated per serving (serves 6):
Calories: 350
Fat: 24g
Protein: 28g
Carbohydrates: 4g
Q&A
1. Can I make this casserole ahead of time?
Yes, you can prepare the casserole up to the baking step and refrigerate it for up to 24 hours. Just add 5 extra minutes to the bake time if starting cold.
2. Can I freeze this dish?
Absolutely. Let it cool completely, wrap tightly in foil or airtight containers, and freeze for up to 3 months. Thaw overnight before reheating.
3. Is this recipe kid-friendly?
Most kids love the cheesy texture and chicken flavor. If you’re concerned about spice, reduce the buffalo sauce or mix it with a little ranch dressing.
4. Can I use canned chicken?
Yes, although fresh or rotisserie chicken offers better texture, canned chicken works in a pinch—just drain it well and shred before mixing.
5. How do I keep the cheese from overcooking?
Cover the casserole with foil for the first 20 minutes, then uncover for the final 10 minutes to get a golden, bubbly top without burning.
Final Thoughts
Spicy, comforting, and totally low-carb, this Keto Buffalo Chicken Casserole is a go-to for our family dinners. Living abroad has taught me to be resourceful in the kitchen, and this dish is proof that you don’t need fancy ingredients to make something crave-worthy. Whether you’re watching carbs or just want something satisfying, this casserole delivers every time.
Hi, I’m Jason—a dad, home cook, and type 2 diabetic living overseas. I created Clean Eats Hub to help people discover simple, delicious, and health-forward meals that support their personal wellness goals. Whether you’re managing blood sugar, pursuing weight loss, or just trying to eat cleaner, I believe healthy food should never feel like a compromise. Here you’ll find real recipes that work for real life—family-tested, flavor-packed, and always nourishing.